Recent
studies by researchers in the Netherlands have found promising results in
preventative therapies for mesothelioma. Using cancer-fighting antigens within
the body's immune system, mesothelioma patients have responded positively in
most cases when treated with the mesothelioma vaccine. The hope is now that
this therapy can be applied to those who may be at risk of developing
mesothelioma in the future, particularly those who have been exposed to
asbestos but have yet to develop asbestos disease.
Monday, April 21, 2014
Mesothelioma Prevention
Mesothelioma
is known only to be caused by exposure to asbestos, a naturally occurring
fibrous mineral that was used for many years as an industrial insulation
component. As such, the best mesothelioma prevention is the avoidance of
exposure to asbestos. However, in recent years, physicians and cancer
specialists have been developing a mesothelioma vaccine that will arm the
body's immune system with cancer fighting anti-bodies and antigens in those who
are at risk for the development of mesothelioma.
Mesothelioma and Women
Many
women that have been diagnosed with mesothelioma had no direct exposure to
asbestos from working in industrial job settings. Instead they discover that
they are victims of second-hand asbestos exposure that occurred while washing
their husband's clothes that came home from work with asbestos fibers on them.
Child Mesothelioma
Childhood
diagnosis of malignant mesothelioma is extremely rare, although it has been
documented. Mesothelioma is known only to be caused by exposure to asbestos and
takes many years following exposure to asbestos to manifest in adults.
Generally speaking, childhood mesothelioma is considered to be unrelated to
asbestos exposure.
Adult Mesothelioma
Mesothelioma
is most common in adults. Adults who have asbestos exposure history are
typically those most at risk for the development of malignant mesothelioma. It
can take many years for those exposed to asbestos exposure to exhibit the
effects of exposure and, as such, mesothelioma is most often diagnosed in older
individuals, often up to 40 years following exposure.
Mesothelioma Latency Period
Typically,
there is a great deal of time between an individual's exposure to asbestos and
the development of asbestos-related health complications. Mesothelioma is
associated with a long-latency period (often 20-50 years) after exposure. Over
a long period of time, lodged asbestos fibers slowly inflame the lung's
external tissue, often serving as a pre-cursor to the development of malignant mesothelioma.
What are Typical Patient Survival Rates Following a Mesothelioma Diagnosis?
As
mesothelioma is often diagnosed in its advanced stages, the prognosis from
mesothelioma is often in the range of a year after diagnosis. If diagnosed
early enough, however, survival may potentially extend over many years. Patient
survival rates are often contingent on the treatments available to the
particular patient.
Does Mesothelioma Occur in a Particular Sex or Racial Demographic More than Another?
Mesothelioma
is much more common in men than women, due mostly to occupational asbestos exposure being more common
among men of industrial labor sites. That is not to say, however, that women
cannot be diagnosed with mesothelioma. In fact, recent evidence suggests that
mesothelioma incidence in women may rise in the coming years as secondary
exposures to asbestos can manifest in the form of a positive mesothelioma diagnosis. Also of note is that
mesothelioma is much less common among African Americans than in Caucasians,
the reasons for which researchers are still investigating.
What is Mesothelioma
Mesothelioma (or,
more precisely, malignant
mesothelioma) is a rare form of cancer that develops from cells of themesothelium,
the protective lining that covers many of the internal organs of the body.
Mesothelioma is most commonly caused by exposure to asbestos.The most common anatomical
site for mesothelioma is the pleura (the outer lining of thelungs and internal chest wall), but it can
also arise in the peritoneum (the lining of the abdominal cavity),
the pericardium (the sac that
surrounds the heart), or the tunica vaginalis (a sac that surrounds the testis).
Most people who develop mesothelioma have worked in jobs
where they inhaled or ingested asbestos fibers, or were exposed to airborne
asbestos dust and fibers in other ways. Washing clothes of a family member who
worked with asbestos also creates a risk for developing mesothelioma. Unlike lung cancer, there seems to be no
association between mesothelioma and tobacco smoking,
but smoking greatly increases the risk of other asbestos-induced cancers.
Signs and symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest
wall), chest wall pain and constitutional signs such as unexplained weight
loss. The diagnosis may be suspected based on chest
X-ray and CT scan findings, but must be confirmed either
by examining serous effusion cytology or with abiopsy (removing a sample of the suspicious
tissue). A thoracoscopy (inserting a tube with a camera into
the chest) can be used to acquire biopsy material, and allows the introduction
of substances such as talc to obliterate the pleural space (a
procedure called pleurodesis),
preventing more fluid from accumulating and pressing on the lung. Despite
treatment withchemotherapy, radiation
therapy or sometimes surgery, mesothelioma carries a poor
prognosis. Research about screening
tests for the early detection of
mesothelioma is ongoing.